个人简介

姓名：赵国平

职称：医学博士，研究员，博士生导师

研究方向：当归四逆汤方证研究

电子邮箱：tguo428@jnu.edu.cn

赵国平，男，汉族，南京中医药大学中医学博士毕业，日本九州大学医学部访问学者、日本国立弘前大学基因研究中心高级访问学者。曾担任南京中医药大学国家中医药管理局中医医史文献重点学科带头人、教育部国家级中医医史文献重点学科带头人。2005年引进至暨南大学，担任暨南大学国家中医药管理局中医老年医学重点学科带头人、暨南大学国家中医药管理局中西医结合基础学术带头人。曾获江苏省青蓝工程优秀青年骨干教师、江苏省333工程学术技术带头人、南京市优秀留学回国人员先进个人、江苏省有突出贡献青年专家，第七批全国老中医药专家学术经验继承指导老师；荣获国家科技进步三等奖、国家中医药管理局中医药基础研究一等奖、江苏省中医药科技进步一等奖、中国政府出版奖。先后主持国家自然科学基金6项，发表论文100余篇，编写专著及教材19部。

更新时间：2024年1月21日

教学/科研成果

1.主持课题（近5年）：

（1） 国家自然科学基金面上-基于 artemin/GFRα3 调控 TRP 通道探讨当归四逆汤镇痛作用机制 （2019-2022，主持）

（2） 国家自然科学基金面上-基于抗炎-神经微循环的交互作用探讨当归四逆汤对坐骨神经损伤的修复机制（2023-2026，主持）

2.发表论文（近3年）：

（1）Zheng Y. C., Zhao, J. J., Chang, S. Q., Zhuang, Z. F., Waimei, S., Li, X., Chen, Z. N., Jing, B., Zhang, D., Guoping Zhao*. β-Sitosterol Alleviates Neuropathic Pain by Affect Microglia Polarization through Inhibiting TLR4/NF-κB Signaling Pathway [J]. Journal of Neuroimmune Pharmacology, 2023.

（2）Zhang D., Li, X., Jing, B., Chen, Z., Shi, H., Zheng, Y., Chang, S., Sun, J., Guoping Zhao*.. alpha-Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair [J]. Phytotherapy Research, 2023, 37(1): 151-62.

（3）Zhang D., Jing, B., Chen, Z. N., Li, X., Shi, H. M., Zheng, Y. C., Chang, S. Q., Gao, L., Guoping Zhao*.. Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting nerve repair via the TLR4/NF-kappaB pathway [J]. CNS Neurosci Ther, 2023.

（4）Si W. M., Li, X., Jing, B., Chang, S. Q., Zheng, Y. C., Chen, Z. N., Guoping Zhao*., Zhang, D*. Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain [J]. Phytotherapy Research, 2023.

（5）Li X., Zhang, D., Shi, H., Jing, B., Chen, Z., Zheng, Y., Chang, S., Gao, L., Guoping Zhao*.. Identification of pyroptosis‑related genes in neuropathic pain based on bioinformatics analysis [J]. Exp Ther Med, 2023, 25(1): 46.

（6）Li X., Shi, H. M., Zhang, D., Jing, B., Chen, Z. N., Zheng, Y. C., Chang, S. Q., Gao, L., Guoping Zhao*.. Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway [J]. Cns Neuroscience & Therapeutics, 2023, 29(9): 2666-79.

（7）Bei Jing Zhen-ni Chen, Wai-mei Si,, Jia-ji Zhao,Guoping Zhao*., DiZhang*. (+)-Catechin alleviates CCI-induced neuropathic pain in rats by modulating the IL34/CSFIR axis and attenuating the Schwann cell-macrophage cascade response in the DRG [J]. Molecular Neurobiology, 2023.

（8）Zhang D., Li, X., Jing, B., Shi, H., Chang, S., Chen, Z., Zheng, Y., Pan, Y., Qian, G., Guoping Zhao*. Identification of pathways and key genes in male late-stage carotid atherosclerosis using bioinformatics analysis [J]. Exp Ther Med, 2022, 24(1): 460.

（9）Zhang D., Jing, B., Li, X., Shi, H. M., Chen, Z. N., Chang, S. Q., Zheng, Y. C., Lin, Y., Pan, Y. W., Sun, J. X., Guoping Zhao*. Antihyperalgesic Effect of Paeniflorin Based on Chronic Constriction Injury in Rats [J]. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy, 2022, 32(3): 375-85.

（10）Zhang D., Jing, B., Chen, Z., Li, X., Shi, H., Zheng, Y., Chang, S., Guoping Zhao*.. Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway [J]. Phytomedicine, 2022, 106: 154420.

（11）Zhang D., Chang, S., Li, X., Shi, H., Jing, B., Chen, Z., Lin, Y., Zheng, Y., Qian, G., Pan, Y., Guoping Zhao*. Therapeutic effect of paeoniflorin on chronic constriction injury of the sciatic nerve via the inhibition of Schwann cell apoptosis [J]. Phytother Res, 2022, 36(6): 2572-82.

（12）Chang S. Q., Li, X., Zheng, Y. C., Shi, H. M., Zhang, D., Jing, B., Chen, Z. N., Qian, G. Q., Guoping Zhao*. Kaempferol exerts a neuroprotective effect to reduce neuropathic pain through TLR4/NF-kappa B signaling pathway [J]. Phytotherapy Research, 2022, 36(4): 1678-91.

（13）Chang S. Q., Huang, Y. L., Zhang, D., Sun, J. X., Yang, B., Lin, Y., Li, X., Jing, B., Shi, H. M., Zheng, Y. C., Zhang, C. L., Chen, F. G., Qian, G. Q., Guoping Zhao*. Mechanism of Ginsenoside Rb1 Modulating the Glycolipid Metabolism in Rats with Metabolic Syndrome [J]. International Journal of Pharmacology, 2022, 18(2): 331-45.

（14）Zhang D., Yang, B., Chang, S. Q., Ma, S. S., Sun, J. X., Yi, L., Li, X., Shi, H. M., Jing, B., Zheng, Y. C., Zhang, C. L., Chen, F. G., Guoping Zhao*. Protective effect of paeoniflorin on H(2)O(2) induced Schwann cells injury based on network pharmacology and experimental validation [J]. Chin J Nat Med, 2021, 19(2): 90-9.

（15）Zhang D., Sun, J., Chang, S., Li, X., Shi, H., Jing, B., Zheng, Y., Lin, Y., Qian, G., Pan, Y., Guoping Zhao*. Protective effect of 18beta-glycyrrhetinic acid against H(2)O(2)-induced injury in Schwann cells based on network pharmacology and experimental validation [J]. Exp Ther Med, 2021, 22(5): 1241.

（16）Zhang D., Chang, S. Q., Jing, B., Li, X., Shi, H. M., Zheng, Y. C., Lin, Y., Chen, Z. N., Qian, G. Q., Pan, Y. W., Guoping Zhao*. Reactive Oxygen Species Are Essential for Vasoconstriction upon Cold Exposure [J]. Oxidative Medicine and Cellular Longevity, 2021, 2021.

（17）Yang B., Ma, S., Zhang, C., Sun, J., Zhang, D., Chang, S., Lin, Y., Guoping Zhao*. Higenamine Attenuates Neuropathic Pain by Inhibition of NOX2/ROS/TRP/P38 Mitogen-Activated Protein Kinase/NF-κB Signaling Pathway [J]. Front Pharmacol, 2021, 12: 716684.

获奖及荣誉

（1）赵国平(4/4); 国家中医药管理局中医药基础研究奖, 国家中医药管理局, 科技进步, 省部一等奖, 1998(彭怀仁; 孙世发; 王旭东; 赵国平)

（2）赵国平(4/4); 国家科技进步三等奖, 中华人民共和国科技部,国家级三等奖, 1999(彭怀仁; 孙世发; 王旭东; 赵国平)

（3）赵国平(1/1); 江苏省要突出贡献中青年专家称号, 江苏省人民政府, 江苏省有突出贡献中青年专家, 省部一等奖, 2005(赵国平)

（4）赵国平 (1/3); 《中药大辞典》第二版获第二届中国出版政府奖图书奖, 国家新闻出版总署, 《中药大 辞典》（第二版）, 省部一等奖, 2010(赵国平; 戴慎; 陈仁寿 ) (科研奖励)

（5）赵国平(1/1) 第七批全国老中医药专家学术经验继承指导老师，2022

学术兼职

广东省中医药学会理事

中华中医药学会中医免疫分会常务理事

中共湛江市委保健委员会保健专家