张迪

研究方向:当归四逆汤方证研究、抑郁症相关方证研究,电子邮箱:dizhang0915@jnu.edu.cn

 


个人介绍

姓名:张迪

职称:讲师

研究方向:当归四逆汤方证研究、抑郁症相关方证研究

电子邮箱:dizhang0915@jnu.edu.cn

个人简介:

张迪,男,中共党员,2023年获中西医结合博士学位。

主要从事中医方证相关研究,聚焦于中枢/外周神经系统/心脑血管系统疾病的机制研

究。主持获批课题2项,参加国家自然科学基金2项,第一作者及共同通讯作者发表SCI

论文14篇,其中中科院1区两篇。担任中国民族医药学会方药量效研究分会理事

  

  

更新时间:2023年12月25日  

 


教学/科研成果

 


1.主持课题:

1)中国博士后科学基金特别资助-站前  

2)国家资助博士后研究人员计划(C类) 

2.参与课题:  

1)国家自然科学基金面上-基于 artemin/GFRα3 调控 TRP 通道探讨当归四逆汤镇痛作用机制 

2)国家自然科学基金面上-基于抗炎-神经微循环的交互作用探讨当归四逆汤对坐骨神经损伤的修复机制

3.发表论文:

[1]Zhang D., Jing, B., Chen, Z. N., Li, X., Shi, H. M., Zheng, Y. C., Chang, S. Q., Gao, L., Zhao, G. P. Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting nerve repair via the TLR4/NF-kappaB pathway [J]. CNS Neurosci Ther, 2023.(中科院1区)

[2]Zhang D., Jing, B., Chen, Z., Li, X., Shi, H., Zheng, Y., Chang, S., Zhao, G. Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway [J]. Phytomedicine, 2022, 106: 154420. (中科院1区)

[3]Zhang D., Yang, B., Chang, S. Q., Ma, S. S., Sun, J. X., Yi, L., Li, X., Shi, H. M., Jing, B., Zheng, Y. C., Zhang, C. L., Chen, F. G., Zhao, G. P. Protective effect of paeoniflorin on H(2)O(2) induced Schwann cells injury based on network pharmacology and experimental validation [J]. Chin J Nat Med, 2021, 19(2): 90-9. (中科院2区)

[4]Zhang D., Chang, S., Li, X., Shi, H., Jing, B., Chen, Z., Lin, Y., Zheng, Y., Qian, G., Pan, Y., Zhao, G. Therapeutic effect of paeoniflorin on chronic constriction injury of the sciatic nerve via the inhibition of Schwann cell apoptosis [J]. Phytother Res, 2022, 36(6): 2572-82. (中科院2区)

[5]Zhang D., Li, X., Jing, B., Chen, Z., Shi, H., Zheng, Y., Chang, S., Sun, J., Zhao, G. alpha-Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair [J]. Phytother Res, 2023, 37(1): 151-62. (中科院2区)

[6]Zhang D., Chang, S. Q., Jing, B., Li, X., Shi, H. M., Zheng, Y. C., Lin, Y., Chen, Z. N., Qian, G. Q., Pan, Y. W., Zhao, G. P. Reactive Oxygen Species Are Essential for Vasoconstriction upon Cold Exposure [J]. Oxidative Medicine and Cellular Longevity, 2021, 2021. (中科院2区)

[7]Zhang D., Sun, J., Yang, B., Ma, S., Zhang, C., Zhao, G. Therapeutic Effect of Tetrapanax papyriferus and Hederagenin on Chronic Neuropathic Pain of Chronic Constriction Injury of Sciatic Nerve Rats Based on KEGG Pathway Prediction and Experimental Verification [J]. Evid Based Complement Alternat Med, 2020, 2020: 2545806.SCI收录)

[8]Zhang D., Sun, J., Chang, S., Li, X., Shi, H., Jing, B., Zheng, Y., Lin, Y., Qian, G., Pan, Y., Zhao, G. Protective effect of 18beta-glycyrrhetinic acid against H(2)O(2)-induced injury in Schwann cells based on network pharmacology and experimental validation [J]. Exp Ther Med, 2021, 22(5): 1241. SCI收录)

[9]Zhang D., Jing, B., Li, X., Shi, H. M., Chen, Z. N., Chang, S. Q., Zheng, Y. C., Lin, Y., Pan, Y. W., Sun, J. X., Zhao, G. P. Antihyperalgesic Effect of Paeniflorin Based on Chronic Constriction Injury in Rats [J]. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy, 2022, 32(3): 375-85. SCI收录)

[10]Zhang D., Li, X., Jing, B., Shi, H., Chang, S., Chen, Z., Zheng, Y., Pan, Y., Qian, G., Zhao, G. Identification of pathways and key genes in male late-stage carotid atherosclerosis using bioinformatics analysis [J]. Exp Ther Med, 2022, 24(1): 460.

[11]Zhang D., Chen, D., Ma, S. S., Bian, W. Y., Xie, F., Huang, M. N., Lin, H. M., Zhan, Q. X., Zhao, G. Effect of Danggui Sini Decoction on the Behaviour and Dorsal Root Ganglion TRP Channel of Neuropathic Pain in CCI Rats [J]. Indian Journal of Pharmaceutical Sciences, 2019, 81(5): 922-32. SCI收录)

[12]Zheng Y. C., Zhao, J. J., Chang, S. Q., Zhuang, Z. F., Waimei, S., Li, X., Chen, Z. N., Jing, B., Zhang, D., Zhao, G. P. β-Sitosterol Alleviates Neuropathic Pain by Affect Microglia Polarization through Inhibiting TLR4/NF-κB Signaling Pathway [J]. Journal of Neuroimmune Pharmacology, 2023. (中科院2区)

[13]Si W. M., Li, X., Jing, B., Chang, S. Q., Zheng, Y. C., Chen, Z. N., Zhao, G. P., Zhang, D. Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain [J]. Phytotherapy Research, 2023. (中科院2区)

[14]Jing B., Chen Z., Si W., Zhao J., Zhao G., Zhang D.. (+)-Catechin alleviates CCI-induced neuropathic pain in rats by modulating the IL34/CSFIR axis and attenuating the Schwann cell-macrophage cascade response in the DRG [J]. Molecular Neurobiology, 2023. (中科院2区)

 


获奖及荣誉

 


暨南大学林道青年医学科学(综合组)优秀奖

博士研究生国奖学金

第四届粤港澳大湾区医学生论坛口头汇报优秀奖

暨南大学优秀毕业生(研究生)


学术兼职

 


中国民族医药学会方药量效研究分会理事